How to do the vinegar-white experiment
The vinegar-white test is a commonly used medical testing method, mainly used for cervical cancer screening and HPV infection diagnosis. It helps doctors quickly identify diseased areas through the reaction of acetic acid solution with abnormal cells. The following are the detailed steps, precautions, and structured organization of related data about the vinegar-white experiment.
1. Principle of vinegar-white experiment
The acetowhitening test uses an acetic acid solution (usually 3%-5%) to react with proteins in abnormal cervical cells, causing the cells to temporarily turn white. This change can be observed under colposcopy, helping doctors locate suspicious lesions.
2. Operation steps of vinegar whitening experiment
| step | Operation content | Things to note |
|---|---|---|
| 1. Preparation | Prepare 3%-5% acetic acid solution, colposcope, sterile cotton swabs, gloves and other tools | Ensure the environment is sterile and avoid cross-infection |
| 2. Patient preparation | The patient is in the cystolithotomy position and the cervix is exposed | Informed consent must be obtained from the patient before operation |
| 3. Apply acetic acid | Dip a cotton swab into the acetic acid solution and apply it evenly on the surface of the cervix | Avoid contact of acetic acid with normal mucosal tissue |
| 4. Observe reactions | Wait 1-2 minutes and use a colposcope to observe changes in the cervix | Record the extent and extent of the blanched area |
| 5. Judgment of results | Determine the possibility of lesions based on indicators such as degree of whitening and border clarity. | Comprehensive evaluation needs to be combined with other inspection results |
3. Interpretation of the results of the vinegar-white experiment
| Result performance | clinical significance | Follow-up suggestions |
|---|---|---|
| Whitens quickly and has clear borders | Highly suspicious of high-grade squamous intraepithelial lesion (HSIL) | Recommended biopsy for diagnosis |
| Slowly whitens, blurred borders | Possible low-grade disease or inflammation | Follow-up observation is recommended |
| No whitening reaction | normal cervical tissue | Just routine screening |
4. Advantages and Disadvantages of the Vinegar White Experiment
advantage:
1. Simple operation and low cost
2. Can quickly screen suspicious lesions
3. Non-radioactive and reusable
shortcoming:
1. Low specificity, false positives may occur
2. Rely on operator experience
3. It cannot replace pathological diagnosis.
5. Precautions for the vinegar-white experiment
1. The best time to check is 3-7 days after menstruation is clean
2. Avoid sexual intercourse and vaginal medication 24 hours before the examination
3. Use with caution in pregnant women
4. It is not suitable to undergo examination during the acute reproductive tract inflammation stage.
6. Clinical application data of vinegar white experiment
| Statistics Project | data | illustrate |
|---|---|---|
| sensitivity | 70%-80% | Detection rate of high-grade lesions |
| specificity | 60%-70% | The ability to differentiate between normal and abnormal tissue |
| positive predictive value | about 75% | Proportion of actual disease among positive results |
7. Alternative methods to the vinegar-white experiment
1.TCT examination:Liquid-based cytology examination with higher accuracy
2.HPV testing:Direct detection of high-risk HPV infection
3.Colposcopy biopsy:gold standard for diagnosis
8. Frequently Asked Questions
Q: Will the vinegar-white test be painful?
A: Generally it does not cause obvious pain, but may cause slight discomfort.
Q: Does a positive test for acetaminophen definitely lead to cancer?
A: Not necessarily. It needs to be combined with other inspections to make a comprehensive judgment.
Q: How often should you do the vinegar-white test?
A: It is recommended that women over 21 years old should be tested every 3 years, and women over 30 years old can be tested with HPV.
As an important method for cervical cancer screening, the vinegar-white test has certain limitations, but it is still of great value in areas with limited resources. It is recommended that women undergo regular cervical cancer screening for early detection and early treatment.
check the details
check the details
en
